|
CITATION:
Axelrod DA, McCullough KP, Brewer ED, Becker BN, Segev DL, Rao PS. Kidney and pancreas transplantation in the United States, 1999-2008: The changing face of living donation. Am J Transplant 2010; 10 (4 part 2): 987-1002
ABSTRACT:
The waiting list for kidney transplantation continued
to grow between 1999 and 2008, from 41 177 to
76 089 candidates. However, active candidates represented
the minority of this increase (36 951–50 624, a
37% change), while inactive candidates increased over
500% (4226–25 465). There were 5966 living donor (LD)
and 10 551 deceased donor (DD) kidney transplants
performed in 2008. The total number of pancreas transplants
peaked at 1484 in 2004 and has declined to 1273.
Although the number of LD transplants increased by
26% from 1999 to 2008, the total number peaked in
2004 at 6647 before declining 10% by 2008. The rate
of LD transplantation continues to vary significantly
as a function of demographic and geographic factors,
including waiting time for DD transplant. Posttransplant
survival remains excellent, and there appears to
be greater use of induction agents and reduced use
of corticosteroids in LD recipients. Significant changes
occurred in the pediatric population, with a dramatic
reduction in the use of LD organs after passage of the
Share 35 rule. Many strategies have been adopted to
reverse the decline in LD transplant rates for all age
groups, including expansion of kidney paired donation,
adoption of laparoscopic donor nephrectomy and use
of incompatible LD.
|
|
|
Arbor Research
Collaborative for Health
315 W. Huron St.
Suite 360
Ann Arbor, MI 48103
USA
Tel: +1 (734) 665-4108
Fax: +1 (734) 665-2103
Contact Us
Get Map
|
|