Study of self-reported symptom clusters may improve the diagnosis and treatment of women with lower urinary tract disorders

Currently, women with lower urinary tract symptoms (LUTS) are treated according to their most troubling symptom. This approach is not always completely successful, as it does not take into account that patients can have multiple symptoms that respond to different treatments.

Describing patients seeking care for lower urinary tract symptoms

The term “lower urinary tract symptoms” (LUTS) includes a wide range of symptoms, including urgency, frequency, dysuria (painful urination), nocturia (excessive nighttime urination), post-void dribbling, and urinary incontinence. Much is still unknown about the effects of LUTS, and treatments often fall short of fully addressing the problem.

What motivates someone to seek treatment for lower urinary tract symptoms?

Lower urinary tract symptoms (LUTS) can have a negative impact on quality of life. Yet not all of those who report having LUTS seek clinical care for their symptoms. In a paper in The Journal of Urology, the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) sought to understand and evaluate reasons why people do or do not seek treatment for LUTS.

The Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)

In 2012, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) created the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) to address gaps in understanding and treating lower urinary tract symptoms (LUTS). LURN is an interdisciplinary consortium-based cooperative research network made up of six clinical research sites and one data coordinating center that aims to change the way we study and treat patients with LUTS. In a newly published paper in the Journal of Urology, the LURN study team presents an overview of the network’s goals.


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